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Nasolabial Fold Fillers: What You Need to Know from Mechanism to Recovery

Nasolabial fold fillers are described as working by using substances such as hyaluronic acid, calcium hydroxyapatite, and poly-L-lactic acid to fill in sunken areas with volume or to stimulate collagen production. The duration and mechanism of action vary depending on the ingredient, and since the effects and how long they last differ from person to person, it's necessary to have a thorough consultation with a specialist before the procedure.

Nasolabial Fold Fillers: What You Need to Know from Mechanism to Recovery · Editorial Image

Nasolabial folds (the grooves running from the sides of the nose to the corners of the mouth) often become more pronounced with age as fat and volume decrease and the skin sags. One of the representative methods used to address this is filler procedures, and the mechanism of action and duration are described differently depending on the ingredient used.

This article summarizes the basic principles of nasolabial fold fillers, the characteristics of each ingredient, the known course of treatment and downtime, and home care after the procedure. Whether to undergo the procedure and which method to use can vary depending on an individual's skin condition and anatomical characteristics, so it's advisable to make that decision through a consultation with a specialist.

표피
피부 가장 바깥층
얕은 층
진피
미세 주름·질감 개선 목적의 얕은 주입이 이뤄지기도 함
중간~깊은 층
피하지방층
볼륨 형성을 목표로 하는 주요 주입 층으로 설명됨
깊은 층
근막·혈관 구조
혈관이 지나는 위험 구조가 위치, 정확한 해부학적 이해가 중요
팔자주름 필러가 작용하는 피부 층의 일반적인 구조 예시

How Do Nasolabial Fold Fillers Work?

Filler procedures are described as working by injecting hyaluronic acid or collagen-related substances into the skin layers to physically fill sunken areas and create volume. Hyaluronic acid fillers, the most widely used type, take advantage of the substance's water-attracting properties to fill volume and are often designed to achieve a relatively natural texture.

Calcium hydroxyapatite is known to provide relatively greater volume and longer-lasting results, while poly-L-lactic acid is described as working not by creating immediate volume but by stimulating collagen production, leading to tissue remodeling over time. For this reason, the term 'collagen production stimulation' or 'tissue remodeling' is more accurate than 'reconstruction' when describing poly-L-lactic acid-based products.

Some cell-level studies have suggested the possibility that hyaluronic acid may stimulate fibroblasts and promote responses related to collagen production through related signaling pathways. However, these are hypothesis-level research findings aimed at explaining the mechanism, and it is difficult to directly connect them to actual procedural effects, as individual responses may vary.

How Long Do the Effects Last — Course and Individual Variation

According to an analysis combining several studies, improvement scores jointly assessed by physicians and patients tended to be relatively high at the 1-month and 6-month marks after the procedure, but tended to decrease by the 12-month mark. This is interpreted as being related to the way filler substances are gradually absorbed or metabolized in the body over time, and the duration of the effect can vary depending on an individual's metabolic rate, lifestyle habits, and the condition of the treated area.

For hyaluronic acid fillers, some studies have reported improvement on wrinkle severity scales at the 6-month follow-up point, but this should also be understood as reference data rather than an absolute figure. It's important to keep in mind that the effects of the procedure, the degree to which they are felt, and how long they last can vary from person to person.

Anatomical Characteristics Worth Knowing About the Treatment Area

The nasolabial fold area, along with the glabella and nose, is mentioned as one of the anatomically risky areas with a relatively complex vascular structure. For this reason, accurate anatomical knowledge and technique during the procedure are said to be especially important.

Among the known complications, the most common are lumps, tenderness, swelling, and bruising at the injection site, most of which are classified as mild reactions that naturally subside over time. On the other hand, vascular occlusion, which can occur rarely, is a serious complication that can lead to tissue ischemia or necrosis, and the nasolabial fold and lip areas have been reported as sites where such vascular occlusion relatively often occurs. That said, the incidence itself is known to be very low among all procedures, and to reduce this risk, it's important to be treated by a medical professional familiar with the anatomical structures and to have a thorough consultation beforehand.

Recovery After the Procedure: Home Care Makes the Difference

Right after the procedure, the injection site may experience temporary swelling or sensitivity, so care that protects the skin barrier and reduces irritation during this period can be helpful. Abiju Cream is designed in two steps: STEP 1 Ultra Cera-Rich, focused on soothing redness and barrier care for the immediate post-procedure and early recovery period, followed by STEP 2 Hydro Re-Boosting for continued deep-hydration care during the later recovery period. However, it cannot be concluded that cosmetics affect the course or duration of the procedure itself, and if there is any damage or abnormal reaction at the treatment site, it's safest to consult with the clinic where the procedure was performed before deciding whether to use them.

FAQ

How long do nasolabial fold fillers last?
The duration can vary depending on the ingredient used as well as individual factors such as metabolic rate and lifestyle habits. Hyaluronic acid fillers are generally known to be gradually absorbed over time, and it's best to check the differences in longevity between ingredients through a consultation with a specialist.
How much downtime is there after a filler procedure?
Temporary swelling, bruising, tenderness, and lumps may occur, and these are generally known to be mild reactions that subside within a few days in most cases. However, since there is individual variation, the recovery period and severity of symptoms may differ from person to person.
I'm worried about side effects from filler procedures. What should I do?
In rare cases, serious complications such as vascular occlusion have been reported, so it's important to be treated by a medical professional who has a thorough understanding of the anatomical structures involved, and to check risk factors through a consultation beforehand. If you notice any unusual symptoms, you should contact the clinic where you had the procedure immediately.
When can I start using cosmetics after the procedure?
This can vary depending on the condition of the treated area and the speed of recovery, so it's difficult to give a one-size-fits-all answer. It's safer to determine the timing based on the guidance of the clinic where you had the procedure, and it's generally recommended to focus on low-irritation soothing and moisturizing products.
Which is better when comparing fillers to other procedures?
Each procedure has different mechanisms, characteristics, and suitable areas or conditions, so it's difficult to determine which is superior across the board. Since the appropriate method varies depending on an individual's skin condition and goals, it's advisable to decide through a consultation with a specialist.

Medically reviewed by 아비쥬의원 의료진. (September 10, 2026)